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The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice

PRMT5 is a type II protein arginine methyltransferase with roles in stem cell biology, reprograming, cancer and neurogenesis. During embryogenesis in the mouse, it was hypothesized that PRMT5 functions with the master germline determinant BLIMP1 to promote primordial germ cell (PGC) specification. U...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Li, Ziwei, Yu, Juehua, Hosohama, Linzi, Nee, Kevin, Gkountela, Sofia, Chaudhari, Sonal, Cass, Ashley A, Xiao, Xinshu, Clark, Amander T
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369312/
https://ncbi.nlm.nih.gov/pubmed/25519955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489319
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