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The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice

PRMT5 is a type II protein arginine methyltransferase with roles in stem cell biology, reprograming, cancer and neurogenesis. During embryogenesis in the mouse, it was hypothesized that PRMT5 functions with the master germline determinant BLIMP1 to promote primordial germ cell (PGC) specification. U...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Li, Ziwei, Yu, Juehua, Hosohama, Linzi, Nee, Kevin, Gkountela, Sofia, Chaudhari, Sonal, Cass, Ashley A, Xiao, Xinshu, Clark, Amander T
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369312/
https://ncbi.nlm.nih.gov/pubmed/25519955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489319
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