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DNA-directed Polymerase Subunits Play a Vital Role in Human Telomeric Overhang Processing

Telomeres consist of TTAGGG repeats bound by the shelterin complex and end with a 3' overhang. In humans, telomeres shorten at each cell division, unless telomerase (TERT) is expressed and able to add telomeric repeats. For effective telomere maintenance, the DNA strand complementary to that ma...

詳細記述

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Diotti, Raffaella, Kalan, Sampada, Matveyenko, Anastasiya, Loayza, Diego
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369185/
https://ncbi.nlm.nih.gov/pubmed/25519149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0381
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