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LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit

DNA damage response pathways are essential for genome stability and cell survival. Specifically, the ATR kinase is activated by DNA replication stress. An early event in this activation is the recruitment and phosphorylation of RPA, a single stranded DNA binding complex composed of three subunits, R...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fowler, Sandy, Maguin, Pascal, Kalan, Sampada, Loayza, Diego
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015067/
https://ncbi.nlm.nih.gov/pubmed/29934626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27919-8
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