Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.

To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1 alpha (PGI-M) and 2,3-dinor-thromboxane B2 (Tx-M) were measured in urine by mass spectrometry during continuing administration of aspirin. To define the relationship of aspir...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	FitzGerald, G A, Oates, J A, Hawiger, J, Maas, R L, Roberts, L J, Lawson, J A, Brash, A R
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1983
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6338043/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110814
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