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Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.

To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1 alpha (PGI-M) and 2,3-dinor-thromboxane B2 (Tx-M) were measured in urine by mass spectrometry during continuing administration of aspirin. To define the relationship of aspir...

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Bibliografiska uppgifter
Huvudupphovsmän: FitzGerald, G A, Oates, J A, Hawiger, J, Maas, R L, Roberts, L J, Lawson, J A, Brash, A R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1983
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC436917/
https://ncbi.nlm.nih.gov/pubmed/6338043
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