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The tyrosine kinase adaptor protein FRS2 is oncogenic and amplified in high-grade serous ovarian cancer
High-grade serous ovarian cancers (HGSOC) are characterized by widespread recurrent regions of copy number gain and loss. Here we interrogated 50 genes that are recurrently amplified in HGSOC and essential for cancer proliferation and survival in ovarian cancer cell lines. FRS2 is one of the 50 gene...
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| Publicado no: | Mol Cancer Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369154/ https://ncbi.nlm.nih.gov/pubmed/25368431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0407 |
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