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Spectrum of variations in dog-1/FANCJ and mdf-1/MAD1 defective Caenorhabditis elegans strains after long-term propagation
BACKGROUND: Whole and partial chromosome losses or gains and structural chromosome changes are hallmarks of human tumors. Guanine-rich DNA, which has a potential to form a G-quadruplex (G(4)) structure, is particularly vulnerable to changes. In Caenorhabditis elegans, faithful transmission of G-rich...
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| Pubblicato in: | BMC Genomics |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369104/ https://ncbi.nlm.nih.gov/pubmed/25880765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1402-y |
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