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Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus

OBJECTIVE: Serine palmitoyltransferase (SPT) catalyzes the condensation of serine and palmitoyl coenzyme A, the first step in the de novo sphingolipid synthesis. Apart from these canonical substrates, SPT can also metabolize alanine and other acyl coenzyme As. This forms a spectrum of atypical sphin...

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Detalles Bibliográficos
Publicado en:BMJ Open Diabetes Res Care
Main Authors: Othman, Alaa, Saely, Christoph H, Muendlein, Axel, Vonbank, Alexander, Drexel, Heinz, von Eckardstein, Arnold, Hornemann, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368929/
https://ncbi.nlm.nih.gov/pubmed/25815206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2014-000073
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