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Thrombolysis with Human Extrinsic (Tissue-Type) Plasminogen Activator in Rabbits with Experimental Jugular Vein Thrombosis. EFFECT OF MOLECULAR FORM AND DOSE OF ACTIVATOR, AGE OF THE THROMBUS, AND ROUTE OF ADMINISTRATION

A simple venous thrombosis model in rabbits was used for the quantitative evaluation of the thrombolytic effect of human extrinsic (tissue-type) plasminogen activator as compared with urokinase. A thrombus was formed in an isolated segment of the jugular vein from a mixture of (125)I-labeled fibrino...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Collen, D., Stassen, J. M., Verstraete, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6681615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110778
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