Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.

The effects of plasminogen activator inhibitor-1 (PAI-1) gene inactivation on hemostasis, thrombosis and thrombolysis were studied in homozygous PAI-1-deficient (PAI-1-/-) mice, generated by homologous recombination in D3 embryonic stem cells. Diluted (10-fold) whole blood clots from PAI-1-/- and fr...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Carmeliet, P, Stassen, J M, Schoonjans, L, Ream, B, van den Oord, J J, De Mol, M, Mulligan, R C, Collen, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116893
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