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Disorders of B cells and helper T cells in the pathogenesis of the immunoglobulin deficiency of patients with ataxia telangiectasia.

The pathogenesis of the immunoglobulin deficiency of 20 patients with ataxia telangiectasia was studied using an in vitro immunoglobulin biosynthesis system. 10 patients had no detectable IgA in their serum as assessed by radial diffusion in agar and 3 had a reduced serum IgA concentration. The peri...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Waldmann, T A, Broder, S, Goldman, C K, Frost, K, Korsmeyer, S J, Medici, M A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6822665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110768
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