Disorders of B cells and helper T cells in the pathogenesis of the immunoglobulin deficiency of patients with ataxia telangiectasia.

The pathogenesis of the immunoglobulin deficiency of 20 patients with ataxia telangiectasia was studied using an in vitro immunoglobulin biosynthesis system. 10 patients had no detectable IgA in their serum as assessed by radial diffusion in agar and 3 had a reduced serum IgA concentration. The peri...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Waldmann, T A, Broder, S, Goldman, C K, Frost, K, Korsmeyer, S J, Medici, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6822665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110768
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