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Conserved movement of TMS11 between occluded conformations of LacY and XylE of the Major Facilitator Superfamily suggests a similar hinge-like mechanism
Δ-distance maps can detect local remodeling that is difficult to accurately determine using superimpositions. TMSs 11 in both LacY and XylE of the Major Facilitator Superfamily (MFS) uniquely contribute the greatest amount of mobile surface area in the outward occluded state, and undergo analogous m...
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| Publicado no: | Proteins |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4368487/ https://ncbi.nlm.nih.gov/pubmed/25586173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24755 |
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