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PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease

The discovery of mutations in genes encoding protein kinase PTEN-induced kinase 1 (PINK1) and E3 ubiquitin ligase Parkin in familial Parkinson's disease and their association with mitochondria provides compelling evidence that mitochondrial dysfunction is a major contributor to neurodegeneratio...

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Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Kazlauskaite, Agne, Muqit, Miratul M K
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368378/
https://ncbi.nlm.nih.gov/pubmed/25345844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13127
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