Triclabendazole Sulfoxide Causes Stage-Dependent Embryolethality in Zebrafish and Mouse In Vitro

BACKGROUND: Fascioliasis and paragonimiasis are widespread foodborne trematode diseases, affecting millions of people in more than 75 countries. The treatment of choice for these parasitic diseases is based on triclabendazole, a benzimidazole derivative which has been suggested as a promising drug t...

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Bibliographic Details
Published in:PLoS One
Main Authors: Boix, Nuria, Teixido, Elisabet, Vila-Cejudo, Marta, Ortiz, Pedro, Ibáñez, Elena, Llobet, Juan M., Barenys, Marta
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368200/
https://ncbi.nlm.nih.gov/pubmed/25793498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121308
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