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Hypoxanthine phosphoribosyltransferase activity in intact fibroblasts from patients with X-linked hyperuricemia.

Discordance between clinical phenotype and the level of a mutant enzyme activity may reflect differences between enzyme function in vivo and that measured by the customary enzyme assays on cell extracts. In the present study, the conversion of hypoxanthine to phosphorylated products was measured in...

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Autores principales: Holland, M J, DiLorenzo, A M, Dancis, J, Balis, M E, Yü, T F, Cox, R P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1976
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC436819/
https://ncbi.nlm.nih.gov/pubmed/932196
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