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Hypoxanthine phosphoribosyltransferase activity in intact fibroblasts from patients with X-linked hyperuricemia.

Discordance between clinical phenotype and the level of a mutant enzyme activity may reflect differences between enzyme function in vivo and that measured by the customary enzyme assays on cell extracts. In the present study, the conversion of hypoxanthine to phosphorylated products was measured in...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Holland, M J, DiLorenzo, A M, Dancis, J, Balis, M E, Yü, T F, Cox, R P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/932196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108430
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