Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults

Antigen-specific multifunctional T cells that secrete interferon-γ, interleukin-2 and tumour necrosis factor-α simultaneously after activation are important for the control of many infections. It is unclear if these CD8(+) T cells are at an early or late stage of differentiation and whether telomere...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Riddell, Natalie E, Griffiths, Stephen J, Rivino, Laura, King, David C B, Teo, Guo H, Henson, Sian M, Cantisan, Sara, Solana, Rafael, Kemeny, David M, MacAry, Paul A, Larbi, Anis, Akbar, Arne N
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368162/
https://ncbi.nlm.nih.gov/pubmed/25314332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12409
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