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Stress-related and homeostatic cytokines regulate Vγ9Vδ2 T-cell surveillance of mevalonate metabolism

The potentially oncogenic mevalonate pathway provides building blocks for protein prenylation and induces cell proliferation and as such is an important therapeutic target. Among mevalonate metabolites, only isopentenyl pyrophosphate (IPP) has been considered to be an immunologically relevant antige...

詳細記述

保存先:
書誌詳細
出版年:Oncoimmunology
主要な著者: Gruenbacher, Georg, Nussbaumer, Oliver, Gander, Hubert, Steiner, Bernhard, Leonhartsberger, Nicolai, Thurnher, Martin
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368140/
https://ncbi.nlm.nih.gov/pubmed/25960933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.953410
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