Stress-related and homeostatic cytokines regulate Vγ9Vδ2 T-cell surveillance of mevalonate metabolism

The potentially oncogenic mevalonate pathway provides building blocks for protein prenylation and induces cell proliferation and as such is an important therapeutic target. Among mevalonate metabolites, only isopentenyl pyrophosphate (IPP) has been considered to be an immunologically relevant antige...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Gruenbacher, Georg, Nussbaumer, Oliver, Gander, Hubert, Steiner, Bernhard, Leonhartsberger, Nicolai, Thurnher, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368140/
https://ncbi.nlm.nih.gov/pubmed/25960933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.953410
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