Differential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors

In many cancers, regulatory T cells (Treg) play a crucial role in suppressing the effector immune response thereby permitting tumor development. Indeed, in mouse models, their depletion can promote the regression of tumors of various origins, including renal cell carcinoma when located subcutaneous...

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Publicat a:Oncoimmunology
Autors principals: Devaud, Christel, Westwood, Jennifer A, Teng, Michele WL, John, Liza B, Yong, Carmen SM, Duong, Connie PM, Smyth, Mark J, Darcy, Phillip K, Kershaw, Michael H
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368122/
https://ncbi.nlm.nih.gov/pubmed/25941590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.963395
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