Differential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors

In many cancers, regulatory T cells (Treg) play a crucial role in suppressing the effector immune response thereby permitting tumor development. Indeed, in mouse models, their depletion can promote the regression of tumors of various origins, including renal cell carcinoma when located subcutaneous...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Devaud, Christel, Westwood, Jennifer A, Teng, Michele WL, John, Liza B, Yong, Carmen SM, Duong, Connie PM, Smyth, Mark J, Darcy, Phillip K, Kershaw, Michael H
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368122/
https://ncbi.nlm.nih.gov/pubmed/25941590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.963395
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