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P25. In vitro evaluation of the anticancer activity of ganetespib in combination with standard chemotherapeutics in small cell lung cancer (SCLC) cell lines

BACKGROUND: Ganetespib (STA-9090) has anticancer activity due to inhibition of the chaperoning activity of HSP90 for oncogenes and other cellular proteins which support malignant growth. Especially, clinical activity as single drug was found in tumors addicted to modified kinases, such as HER2, ALK,...

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I publikationen:Transl Lung Cancer Res
Huvudupphovsmän: Hamilton, Gerhard, Rath, Barbara, Maritschnegg, Elisabeth, Zeillinger, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Pioneer Bioscience Publishing Company 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367771/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2014.AB037
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