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P25. In vitro evaluation of the anticancer activity of ganetespib in combination with standard chemotherapeutics in small cell lung cancer (SCLC) cell lines
BACKGROUND: Ganetespib (STA-9090) has anticancer activity due to inhibition of the chaperoning activity of HSP90 for oncogenes and other cellular proteins which support malignant growth. Especially, clinical activity as single drug was found in tumors addicted to modified kinases, such as HER2, ALK,...
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| Gepubliceerd in: | Transl Lung Cancer Res |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Pioneer Bioscience Publishing Company
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367771/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2218-6751.2014.AB037 |
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