Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Pubblicato in:Front Physiol
Autori principali: Adeniran, Ismail, MacIver, David H., Hancox, Jules C., Zhang, Henggui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367530/
https://ncbi.nlm.nih.gov/pubmed/25852567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00078
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