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Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study

Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle. Studies from clinical electrophysiology and animal experiments have found that HFpEF is associated with impair...

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Vydáno v:Front Physiol
Hlavní autoři: Adeniran, Ismail, MacIver, David H., Hancox, Jules C., Zhang, Henggui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367530/
https://ncbi.nlm.nih.gov/pubmed/25852567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00078
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