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Increased Culture Density Is Linked to Decelerated Proliferation, Prolonged G(1) Phase, and Enhanced Propensity for Differentiation of Self-Renewing Human Pluripotent Stem Cells
Human pluripotent stem cells (hPSCs) display a very short G(1) phase and rapid proliferation kinetics. Regulation of the cell cycle, which is linked to pluripotency and differentiation, is dependent on the stem cell environment, particularly on culture density. This link has been so far empirical an...
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| Publicado no: | Stem Cells Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367496/ https://ncbi.nlm.nih.gov/pubmed/25405279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0384 |
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