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The Additive Damage Model: a Mathematical Model for Cellular Responses to Drug Combinations
Mathematical models to describe dose-dependent cellular responses to drug combinations are an essential component of computational simulations for predicting therapeutic responses. Here, a new model, the additive damage model, is introduced and tested in cases where varying concentrations of two dru...
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| Veröffentlicht in: | J Theor Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367491/ https://ncbi.nlm.nih.gov/pubmed/24799130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.04.032 |
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