Disrupted Functional and Structural Networks in Cognitively Normal Elderly Subjects with the APOE ɛ4 Allele

As the Apolipoprotein E (APOE) ɛ4 allele is a major genetic risk factor for sporadic Alzheimer's disease (AD), which has been suggested as a disconnection syndrome manifested by the disruption of white matter (WM) integrity and functional connectivity (FC), elucidating the subtle brain structur...

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Pubblicato in:Neuropsychopharmacology
Autori principali: Chen, Yaojing, Chen, Kewei, Zhang, Junying, Li, Xin, Shu, Ni, Wang, Jun, Zhang, Zhanjun, Reiman, Eric M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367462/
https://ncbi.nlm.nih.gov/pubmed/25403724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.302
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