DNA Induces Conformational Changes in a Recombinant Human Minichromosome Maintenance Complex

ATP-dependent DNA unwinding activity has been demonstrated for recombinant archaeal homohexameric minichromosome maintenance (MCM) complexes and their yeast heterohexameric counterparts, but in higher eukaryotes such as Drosophila, MCM-associated DNA helicase activity has been observed only in the c...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Hesketh, Emma L., Parker-Manuel, Richard P., Chaban, Yuriy, Satti, Rabab, Coverley, Dawn, Orlova, Elena V., Chong, James P. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367295/
https://ncbi.nlm.nih.gov/pubmed/25648893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.622738
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