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Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing

Tumor suppressor genes BRCA1 and BRCA2 are the two main breast and ovarian cancer susceptibility genes, and their genetic testing has been used to evaluate the risk of hereditary breast and ovarian cancer (HBOC). While several studies have reported the prevalence of BRCA1 and BRCA2 mutations in Japa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Genet Genomic Med
मुख्य लेखकों: Hirotsu, Yosuke, Nakagomi, Hiroshi, Sakamoto, Ikuko, Amemiya, Kenji, Mochizuki, Hitoshi, Omata, Masao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367084/
https://ncbi.nlm.nih.gov/pubmed/25802882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.120
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