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Detection of BRCA1 and BRCA2 germline mutations in Japanese population using next-generation sequencing
Tumor suppressor genes BRCA1 and BRCA2 are the two main breast and ovarian cancer susceptibility genes, and their genetic testing has been used to evaluate the risk of hereditary breast and ovarian cancer (HBOC). While several studies have reported the prevalence of BRCA1 and BRCA2 mutations in Japa...
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| Publicado no: | Mol Genet Genomic Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367084/ https://ncbi.nlm.nih.gov/pubmed/25802882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.120 |
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