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Synergistic effects of bombesin and epidermal growth factor on cancers.

Bombesin and gastrin-releasing peptide act as autocrine mitogens in various cancers. Bombesin antagonist RC-3095 inhibited growth in some cancers and slowed the progression of premalignant lesions, possibly by down-regulating epidermal growth factor (EGF) receptors. Since the EGF receptor mitogen re...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Liebow, C, Crean, D H, Lee, M T, Kamer, A R, Mang, T S, Schally, A V
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8170991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3804
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