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Treatment of nitrosamine-induced pancreatic tumors in hamsters with analogs of somatostatin and luteinizing hormone-releasing hormone.

Pancreatic ductal adenocarcinoma was induced in female Syrian golden hamsters by injecting N-nitrosobis(2-oxopropyl)amine (BOP) once a week at a dose of 10 mg per kg of body weight for 18 weeks. Hamsters were then treated with somatostatin analog D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (RC-160) or w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Paz-Bouza, J I, Redding, T W, Schally, A V
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2881296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.1112
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