Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. I. Penetration of enzyme into rabbit articular cartilage and release of 35SO4-labeled material from the tissue.

The present work was undertaken to explore the effect of two purified neutral proteases derived from human peripheral blood polymorphonuclear leukocytes (PMN) on articular cartilage as a model of joint injury. Human leukocyte elastase and chymotrypsin-like enzyme, purified by affinity chromatography...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Janoff, A, Feinstein, G, Malemud, C J, Elias, J M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1976
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436694/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/129482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108317
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