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Degradation of cartilage proteoglycan by human leukocyte granule neutral proteases--a model of joint injury. I. Penetration of enzyme into rabbit articular cartilage and release of 35SO4-labeled material from the tissue.

The present work was undertaken to explore the effect of two purified neutral proteases derived from human peripheral blood polymorphonuclear leukocytes (PMN) on articular cartilage as a model of joint injury. Human leukocyte elastase and chymotrypsin-like enzyme, purified by affinity chromatography...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Janoff, A, Feinstein, G, Malemud, C J, Elias, J M
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1976
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/129482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108317
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