DNA Copy Number Control Through Inhibition of Replication Fork Progression

Proper control of DNA replication is essential to ensure faithful transmission of genetic material and to prevent chromosomal aberrations that can drive cancer progression and developmental disorders. DNA replication is regulated primarily at the level of initiation and is under strict cell cycle re...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Nordman, Jared T., Kozhevnikova, Elena N., Verrijzer, C. Peter, Pindyurin, Alexey V., Andreyeva, Evgeniya N., Shloma, Victor V., Zhimulev, Igor F., Orr-Weaver, Terry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366648/
https://ncbi.nlm.nih.gov/pubmed/25437540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.005
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