Developmental control of gene copy number by repression of replication initiation and fork progression

Precise DNA replication is crucial for genome maintenance, yet this process has been inherently difficult to study on a genome-wide level in untransformed differentiated metazoan cells. To determine how metazoan DNA replication can be repressed, we examined regions selectively under-replicated in Dr...

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Bibliographic Details
Main Authors: Sher, Noa, Bell, George W., Li, Sharon, Nordman, Jared, Eng, Thomas, Eaton, Matthew L., MacAlpine, David M., Orr-Weaver, Terry L.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246207/
https://ncbi.nlm.nih.gov/pubmed/22090375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.126003.111
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