Multidrug resistance-selective antiproliferative activity of Piper amide alkaloids and synthetic analogues

Twenty-five amide alkaloids (1–25) from Piper boehmeriifolium and 10 synthetic amide alkaloid derivatives (39–48) were evaluated for antiproliferative activity against eight human tumor cell lines, including chemosensitive and multidrug-resistant (MDR) cell lines. The results suggested tumor type-se...

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Pubblicato in:Bioorg Med Chem Lett
Autori principali: Wang, Yue-Hu, Goto, Masuo, Wang, Li-Ting, Hsieh, Kan-Yen, Morris-Natschke, Susan L., Tang, Gui-Hua, Long, Chun-Lin, Lee, Kuo-Hsiung
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366620/
https://ncbi.nlm.nih.gov/pubmed/25241925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.08.063
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