Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia

Despite recent advances in the cure rate of acute lymphoblastic leukaemia (ALL), the prognosis for patients with relapsed ALL remains poor. Here we identify FOXM1 as a candidate responsible for an aggressive clinical course. We show that FOXM1 levels peak at the pre-B-cell receptor checkpoint but ar...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Buchner, Maike, Park, Eugene, Geng, Huimin, Klemm, Lars, Flach, Johanna, Passegué, Emmanuelle, Schjerven, Hilde, Melnick, Ari, Paietta, Elisabeth, Kopanja, Dragana, Raychaudhuri, Pradip, Müschen, Markus
フォーマット: Artigo
言語:Inglês
出版事項: Nature Pub. Group 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366523/
https://ncbi.nlm.nih.gov/pubmed/25753524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7471
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