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Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1

The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain, including progenitor division and neuronal migration. Here we show that Cenpj, also known as CPAP, a microcephaly gene, is a transcriptional target of Ascl1 in the embryonic cerebral cortex. We have characteri...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Garcez, Patricia P., Diaz-Alonso, Javier, Crespo-Enriquez, Ivan, Castro, Diogo, Bell, Donald, Guillemot, François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366522/
https://ncbi.nlm.nih.gov/pubmed/25753651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7474
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