Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1

The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain, including progenitor division and neuronal migration. Here we show that Cenpj, also known as CPAP, a microcephaly gene, is a transcriptional target of Ascl1 in the embryonic cerebral cortex. We have characteri...

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Vydáno v:Nat Commun
Hlavní autoři: Garcez, Patricia P., Diaz-Alonso, Javier, Crespo-Enriquez, Ivan, Castro, Diogo, Bell, Donald, Guillemot, François
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366522/
https://ncbi.nlm.nih.gov/pubmed/25753651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7474
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