Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism. GLDC mutations cause a rare recessive disease non-ketotic hyperglycinemia (NKH). Mutations have also been identified in patients with neural tub...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Pai, Yun Jin, Leung, Kit-Yi, Savery, Dawn, Hutchin, Tim, Prunty, Helen, Heales, Simon, Brosnan, Margaret E., Brosnan, John T., Copp, Andrew J., Greene, Nicholas D.E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366506/
https://ncbi.nlm.nih.gov/pubmed/25736695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7388
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk