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Structure, Dynamics, and Interaction of Mycobacterium tuberculosis (Mtb) DprE1 and DprE2 Examined by Molecular Modeling, Simulation, and Electrostatic Studies

The enzymes decaprenylphosphoryl-β-D-ribose oxidase (DprE1) and decaprenylphosphoryl-β-D-ribose-2-epimerase (DprE2) catalyze epimerization of decaprenylphosporyl ribose (DPR) todecaprenylphosporyl arabinose (DPA) and are critical for the survival of Mtb. Crystal structures of DprE1 so far reported d...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Bhutani, Isha, Loharch, Saurabh, Gupta, Pawan, Madathil, Rethi, Parkesh, Raman
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366402/
https://ncbi.nlm.nih.gov/pubmed/25789990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119771
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