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Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice.

We investigated the mechanism of taurinuria in three inbred strains of mice: A/J, a normal taurine excretor (taut+); and two hypertaurinuric (taut-) strains, C57BL/6J and PRO/Re. Plasma taurine is comparable in the three strains (approximately 0.5 mM), but taurinuria is 10-fold greater in taut- anim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Chesney, R W, Scriver, C R, Mohyuddin, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1976
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC436638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1245598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108258
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