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Localization of the membrane defect in transepithelial transport of taurine by parallel studies in vivo and in vitro in hypertaurinuric mice.

We investigated the mechanism of taurinuria in three inbred strains of mice: A/J, a normal taurine excretor (taut+); and two hypertaurinuric (taut-) strains, C57BL/6J and PRO/Re. Plasma taurine is comparable in the three strains (approximately 0.5 mM), but taurinuria is 10-fold greater in taut- anim...

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Autori principali: Chesney, R W, Scriver, C R, Mohyuddin, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1976
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC436638/
https://ncbi.nlm.nih.gov/pubmed/1245598
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