Pathogenic E. coli Exploits SslE Mucinase Activity to Translocate through the Mucosal Barrier and Get Access to Host Cells

SslE is a zinc-metalloprotease involved in the degradation of mucin substrates and recently proposed as a potential vaccine candidate against pathogenic E. coli. In this paper, by exploiting a human in vitro model of mucus-secreting cells, we demonstrated that bacteria expressing SslE have a metabol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Valeri, Maria, Rossi Paccani, Silvia, Kasendra, Magdalena, Nesta, Barbara, Serino, Laura, Pizza, Mariagrazia, Soriani, Marco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366376/
https://ncbi.nlm.nih.gov/pubmed/25789808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117486
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