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RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation

Mice with epidermal deletion of JunB transcription factor displayed a psoriasis-like inflammation. The relevance of these findings to humans and the mechanisms mediating JunB function are not fully understood. Here, we demonstrate that impaired JunB function via gene silencing or overexpression of a...

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Detaylı Bibliyografya
Yayımlandı:J Invest Dermatol
Asıl Yazarlar: Zhang, Xiaoling, Jin, Jane Y., Wu, Joseph, Qin, Xiaoxia, Streilein, Robert, Hall, Russell P., Zhang, Jennifer Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366298/
https://ncbi.nlm.nih.gov/pubmed/25501661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.519
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