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Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria
In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyond. These proteins include numerous bacterial virulence factors. Thus, bacterial enzymes that promote disulfide bond formation represent targets for compounds inhibiting bacterial virulence. Here, we...
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| Published in: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366281/ https://ncbi.nlm.nih.gov/pubmed/25686372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1752 |
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