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High-Resolution Sequence-Function Mapping of Full-Length Proteins
Comprehensive sequence-function mapping involves detailing the fitness contribution of every possible single mutation to a gene by comparing the abundance of each library variant before and after selection for the phenotype of interest. Deep sequencing of library DNA allows frequency reconstruction...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366243/ https://ncbi.nlm.nih.gov/pubmed/25790064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118193 |
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