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Liver Inflammation and Metabolic Signaling in Apc(Min/+) Mice: The Role of Cachexia Progression
The Apc(Min/+) mouse exhibits an intestinal tumor associated loss of muscle and fat that is accompanied by chronic inflammation, insulin resistance and hyperlipidemia. Since the liver governs systemic energy demands through regulation of glucose and lipid metabolism, it is likely that the liver is a...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366213/ https://ncbi.nlm.nih.gov/pubmed/25789991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119888 |
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