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Gut Barrier Dysfunction in the Apc(Min/+) Mouse Model of Colon Cancer Cachexia
BACKGROUND: The Apc(Min/+) mouse, an animal model of colorectal cancer and cachexia, has a heterologous mutation in the Apc tumor suppressor gene, predisposing the mouse to intestinal and colon tumor development. This mouse develops intestinal polyps by ~4 weeks of age, and loses body weight gradual...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205242/ https://ncbi.nlm.nih.gov/pubmed/21914473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.08.010 |
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